![]() Use 0.1N sterile HCl supplied by the generator manufacturer. Prepare a syringe containing 5 mL of 0.1 N sterile HCl, to be used for elution of the GalliaPharm Set the temperature of the shielded dry bath to 203 ☏ (95 ☌), and wait for the temperature to reach the set point and stabilize.ĭ. Use suitable shielding to reduce radiation exposure.Ĭ. Prepare Ga 68 dotatate for intravenous injection according to the following aseptic procedure (see above diagram):Ī. Of Ge 68 potentially present in generator eluate. The accessory cartridge reduces the amount Vial 2 (buffer vial) contains: 60 mg formic acid 56.5 mg sodium hydroxide and water for injection.Īccessory cartridge contains: 660 mg porous silica. Vial 1 (reaction vial with lyophilized powder) contains: 40 mcg dotatate, 5 mcg 1,10-phenanthroline Has been established only when using a Ga 68 chloride solution eluted from the GalliaPharm generator. The safety and efficacy of the Ga 68 DOTATATE injection drug product prepared from the NETSPOT kit ![]() GalliaPharm Ge 68/Ga 68 generator (“GalliaPharm generator”) is not supplied with the NETSPOT kit. Ziegler GalliaPharm Germanium 68/Gallium 68 (Ge 68/Ga 68) generator. (3) ] which allows for direct preparation of Ga 68 DOTATATE injection with the eluate from an Eckert & The NETSPOT kit is supplied as 2 vials and an accessory cartridge [see Dosage Forms and Strengths Here is an example of three generators linked to an accessory cartridgeĭrug Preparation (link to entire package insert).Following an elution of 68Ga of 60 mCi, how long would you have to wait to get an additional 45 mCi?.T1/2 of 68Ge is 271 days and the T1/2 of 68Ga is 68 minutes.Via a cyclotron 68Ge is made: 68Zn(p,n) 68Ga.Currently only DOTATATE has been approved by the FDG (June 2016) A new 68Ga imaging agent can be labeled to DOTATATE, DOTATOC, or DOTANOC.We will first explore the imaging of, with PET and then continue with therapy and treatment. While we are familiar with the use of MIBG and Octreotide PET imaging and therapy has now entered the nuclear arena to evaluate and treat neuroendocrine tumors (NET). Neuroendocrine Tumors - Diagnostic and Treatment
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